Got two sets of Polk db6501 which will be powered by two MTX Pro 504 4-channel amps. Would it be ideal/beneficial to bridge the amp into two channel at 100Wrms just to maximize the power handling capability of the speakers?

Polk Audio db6501 specs:
* http://www.polkaudio.com/caraudio/db/index.php?s=db6501

MTX Pro 504 4-channel output amp specs:
* 25 Watts RMS per channel x 4 into 4 ohms @ 0.1% THD 20-20,000 Hz
* 50 Watts RMS per channel x 4 into 2 ohms @ 0.3% THD 20-20,000 Hz
* 100 Watts RMS per channel x 2 into 4 ohms @ 0.1% THD 20-20,000 Hz
* 200 Watts RMS Dynamic Power(IHF 202) Bridged into 4 ohms

 

The short answer is yes, as 25W per side is rather on the weak side. Bridge them and don't look back. I would not recommend running your mids and tweets below 4 ohms. GL