GYPSY60

I just bought a ford f-150 lariat and am looking to put a new system in it. For the subs im going to put them in a sub box behind the rear seat and the amp or amps under other seats or behind the rear seat. I have 4000-4500$ in which to spend on this. 5000 if needed. I would like the best possible system I could get for this price. If anyone could help me out that would be great because im new to this.
PS. I would like 2 subs preferablly 12 inch.